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RGR Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27821N-1 50ul / $395
APR27821N-2 100ul / $495
APR27821N-3 200ul / $595

RGR Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27821N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>G protein signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RGR Polyclonal Antibody.

Molecular Weight

Calculated MW: 27kDa/31kDa/32kDa Observed MW: 32kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human RGR (NP_002912.2).

Cross Reactivity

Human,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

RGR; RP44; retinal G protein coupled receptor

Images

Western blot analysis of extracts of rat spinal cord, using RGR antibody.

Specification

Quantity

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