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PRSS2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27819N-1 50ul / $395
APR27819N-2 100ul / $495
APR27819N-3 200ul / $595

PRSS2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27819N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Ubiquitin

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRSS2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 26kDa Observed MW: 26kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PRSS2 (NP_002761.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.

Synonyms

PRSS2; TRY2; TRY8; TRYP2; trypsin-2

Images

Western blot analysis of extracts of various cell lines, using PRSS2 antibody.

Specification

Quantity

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