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OCT4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27816N-1 50ul / $395
APR27816N-2 100ul / $495
APR27816N-3 200ul / $595

OCT4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27816N

Product Type

Polyclonal Antibodies

Field of Research

Stem Cells>Embryonic Stem Cells

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality OCT4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 30kDa/38kDa Observed MW: 50kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human OCT4

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

Synonyms

POU5F1; OCT3; OCT4; OTF-3; OTF3; OTF4; Oct-3; Oct-4; POU class 5 homeobox 1

Images

Western blot analysis of extracts of various cell lines, using OCT4 antibody.

Immunohistochemistry of paraffin-embedded human brain cancer using OCT4 antibody.

Specification

Quantity

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