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VPS37A Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27757N-1 50ul / $395
APR27757N-2 100ul / $495
APR27757N-3 200ul / $595

VPS37A Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27757N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VPS37A Polyclonal Antibody.

Molecular Weight

Calculated MW: 20kDa/41kDa/44kDa Observed MW: 44kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human VPS37A (NP_689628.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.

Synonyms

VPS37A; HCRP1; PQBP2; SPG53; VPS37A, ESCRT-I subunit

Images

Western blot analysis of extracts of various cell lines, using VPS37A antibody.

Immunohistochemistry of paraffin-embedded rat brain using VPS37A antibody.

Immunohistochemistry of paraffin-embedded mouse stomach using VPS37A antibody.

Specification

Quantity

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