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CHRFAM7A Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27749N-1 50ul / $395
APR27749N-2 100ul / $495
APR27749N-3 200ul / $595

CHRFAM7A Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27749N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CHRFAM7A Polyclonal Antibody.

Molecular Weight

Calculated MW: 46kDa Observed MW: 46kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CHRFAM7A (NP_647536.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.

Synonyms

CHRFAM7A; CHRNA7; CHRNA7-DR1; D-10; CHRNA7-FAM7A fusion protein

Images

Western blot analysis of extracts of various cell lines, using CHRFAM7A antibody.

Immunohistochemistry of paraffin-embedded rat brain using CHRFAM7A antibody.

Immunohistochemistry of paraffin-embedded rat kidney using CHRFAM7A antibody.

Specification

Quantity

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