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ATG4D Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27747N-1 50ul / $395
APR27747N-2 100ul / $495
APR27747N-3 200ul / $595

ATG4D Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27747N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Autophagy

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATG4D Polyclonal Antibody.

Molecular Weight

Calculated MW: 16kDa/52kDa Observed MW: 53kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ATG4D (NP_116274.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants.

Synonyms

ATG4D; APG4-D; APG4D; AUTL4; cysteine protease ATG4D

Images

Western blot analysis of extracts of various cell lines, using ATG4D antibody.

Immunofluorescence analysis of U2OS cells using ATG4D antibody.

Specification

Quantity

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