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PAK6 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27730N-1 50ul / $395
APR27730N-2 100ul / $495
APR27730N-3 200ul / $595

PAK6 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27730N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>Kinase

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PAK6 Polyclonal Antibody.

Molecular Weight

Calculated MW: 69kDa/74kDa Observed MW: 75kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PAK6 (NP_064553.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.

Synonyms

PAK6; PAK5; p21 (RAC1) activated kinase 6

Images

Western blot analysis of extracts of various cell lines, using PAK6 antibody.

Immunohistochemistry of paraffin-embedded human brain cancer using PAK6 antibody.

Specification

Quantity

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