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FBXW11 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27696N-1 50ul / $395
APR27696N-2 100ul / $495
APR27696N-3 200ul / $595

FBXW11 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27696N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FBXW11 Polyclonal Antibody.

Molecular Weight

Calculated MW: 58kDa/60kDa/62kDa Observed MW: 62kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human FBXW11 (NP_387448.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Product Description

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.

Synonyms

FBXW11; BTRC2; BTRCP2; FBW1B; FBXW1B; Fbw11; Hos; F-box/WD repeat-containing protein 11

Images

Western blot analysis of extracts of various cell lines, using FBXW11 antibody.

Immunohistochemistry of paraffin-embedded mouse lung using FBXW11 antibody.

Immunofluorescence analysis of A549 cells using FBXW11 antibody.

Specification

Quantity

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