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KDM5B Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27686N-1 50ul / $395
APR27686N-2 100ul / $495
APR27686N-3 200ul / $595

KDM5B Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27686N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Epigenetic writers and erasers of core Histones

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KDM5B Polyclonal Antibody.

Molecular Weight

Calculated MW: 175kDa/179kDa Observed MW: 176kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human KDM5B (NP_006609.3).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants.

Synonyms

KDM5B; CT31; JARID1B; PLU-1; PLU1; PPP1R98; PUT1; RBBP2H1A; RBP2-H1; lysine demethylase 5B

Images

Western blot analysis of extracts of various cell lines, using KDM5B antibody.

Specification

Quantity

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