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BAG2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27678N-1 50ul / $395
APR27678N-2 100ul / $495
APR27678N-3 200ul / $595

BAG2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27678N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BAG2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 20kDa/23kDa Observed MW: 24kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human BAG2 (NP_004273.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Synonyms

BAG2; BAG-2; dJ417I1.2; BCL2 associated athanogene 2

Images

Western blot analysis of extracts of various cell lines, using BAG2 antibody.

Immunohistochemistry of paraffin-embedded human kidney using BAG2 antibody.

Immunofluorescence analysis of U2OS cells using BAG2 antibody.

Specification

Quantity

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