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ADAM15 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27671N-1 50ul / $395
APR27671N-2 100ul / $495
APR27671N-3 200ul / $595

ADAM15 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27671N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Adhesion

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ADAM15 Polyclonal Antibody.

Molecular Weight

Calculated MW: 55kDa/68kDa/83-92kDa Observed MW: 93kDa

Species Reactivity

Rabbit

Immunogen

Recombinant protein of human ADAM15

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Synonyms

ADAM15; MDC15; ADAM metallopeptidase domain 15

Images

Western blot analysis of extracts of various cell lines, using ADAM15 antibody.

Immunofluorescence analysis of HeLa cells using ADAM15 Polyclonal Antibody.

Specification

Quantity

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