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SRF Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27646N-1 50ul / $395
APR27646N-2 100ul / $495
APR27646N-3 200ul / $595

SRF Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27646N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Heart

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SRF Polyclonal Antibody.

Molecular Weight

Calculated MW: 51kDa Observed MW: 67kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human SRF

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

SRF; MCM1; serum response factor

Images

Western blot analysis of extracts of various cell lines, using SRF antibody.

Specification

Quantity

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