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MAP2K4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27640N-1 50ul / $395
APR27640N-2 100ul / $495
APR27640N-3 200ul / $595

MAP2K4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27640N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>B Cell Receptor Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAP2K4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 44kDa/45kDa Observed MW: 44kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human MAP2K4

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF,IP

Dilution

WB 1:1000 - 1:4000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.

Synonyms

MAP2K4; JNKK; JNKK1; MAPKK4; MEK4; MKK4; PRKMK4; SAPKK-1; SAPKK1; SEK1; SERK1; SKK1; mitogen-activated protein kinase kinase 4

Images

Western blot analysis of extracts of various cell lines, using MAP2K4 antibody.

Immunohistochemistry of paraffin-embedded human kidney using MAP2K4 antibody.

Immunofluorescence analysis of U2OS cells using MAP2K4 antibody.

Specification

Quantity

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