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KRT6B Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27615N-1 50ul / $395
APR27615N-2 100ul / $495
APR27615N-3 200ul / $595

KRT6B Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27615N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KRT6B Polyclonal Antibody.

Molecular Weight

Calculated MW: 60kDa Observed MW: 60kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human KRT6B (NP_005546.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Synonyms

KRT6B; CK-6B; CK6B; K6B; KRTL1; PC2; PC4; keratin 6B

Images

Western blot analysis of extracts of mouse eye, using KRT6B antibody.

Immunofluorescence analysis of U2OS cells using KRT6B antibody.

Specification

Quantity

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