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FANCM Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27536N-1 50ul / $395
APR27536N-2 100ul / $495
APR27536N-3 200ul / $595

FANCM Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27536N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>DNA Damage & Repair

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FANCM Polyclonal Antibody.

Molecular Weight

Calculated MW: 75kDa/229kDa/232kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human FANCM (NP_065988.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M. Alternative splicing results in multiple transcript variants.

Synonyms

FANCM; FAAP250; KIAA1596; Fanconi anemia group M protein

Images

Immunofluorescence analysis of A549 cells using FANCM antibody.

Specification

Quantity

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