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DAZ2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27534N-1 50ul / $395
APR27534N-2 100ul / $495
APR27534N-3 200ul / $595

DAZ2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27534N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DAZ2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 41kDa/60kDa/63kDa Observed MW: 63kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human DAZ2 (NP_001005785.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

DAZ2; pDP1678; deleted in azoospermia 2

Images

Western blot analysis of extracts of mouse testis, using DAZ2 antibody.

Specification

Quantity

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