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MDH1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27503N-1 50ul / $395
APR27503N-2 100ul / $495
APR27503N-3 200ul / $595

MDH1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27503N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Carbohydrate metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MDH1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 27kDa/36kDa/38kDa Observed MW: 36kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human MDH1 (NP_005908.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6.

Synonyms

MDH1; HEL-S-32; MDH-s; MDHA; MGC:1375; MOR2; malate dehydrogenase 1

Images

Western blot analysis of extracts of various cell lines, using MDH1 antibody.

Specification

Quantity

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