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LDB3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27414N-1 50ul / $395
APR27414N-2 100ul / $495
APR27414N-3 200ul / $595

LDB3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27414N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LDB3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 30kDa/35kDa/42kDa/50kDa/66kDa/77kDa/78kDa Observed MW: 50kDa/90kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human LDB3 (NP_001073585.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.

Synonyms

LDB3; CMD1C; CMH24; CMPD3; CYPHER; LDB3Z1; LDB3Z4; LVNC3; MFM4; ORACLE; PDLIM6; ZASP; LIM domain binding 3

Images

Western blot analysis of extracts of various cell lines, using LDB3 antibody.

Immunofluorescence analysis of human placenta cells using LDB3 antibody.

Immunofluorescence analysis of human placenta cells using LDB3 antibody.

Specification

Quantity

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