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CYP2C18 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27383N-1 50ul / $395
APR27383N-2 100ul / $495
APR27383N-3 200ul / $595

CYP2C18 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27383N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Drug metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYP2C18 Polyclonal Antibody.

Molecular Weight

Calculated MW: 48kDa/55kDa Observed MW: 50kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CYP2C18 (NP_000763.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

CYP2C18; CPCI; CYP2C; CYP2C17; P450-6B/29C; P450IIC17; cytochrome P450 2C18

Images

Western blot analysis of extracts of various cell lines, using CYP2C18 antibody.

Immunohistochemistry of paraffin-embedded human liver cancer using CYP2C18 antibody.

Immunohistochemistry of paraffin-embedded mouse liver using CYP2C18 antibody.

Specification

Quantity

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