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PPAN Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27341N-1 50ul / $395
APR27341N-2 100ul / $495
APR27341N-3 200ul / $595

PPAN Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27341N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>G protein signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PPAN Polyclonal Antibody.

Molecular Weight

Calculated MW: 51kDa/53kDa/58kDa Observed MW: 53kDa/55kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PPAN (NP_064615.3).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.

Synonyms

PPAN; BXDC3; SSF; SSF-1; SSF1; SSF2; suppressor of SWI4 1 homolog

Images

Western blot analysis of extracts of various cell lines, using PPAN Antibody.

Immunohistochemistry of paraffin-embedded human prostate using PPAN antibody.

Immunohistochemistry of paraffin-embedded human stomach using PPAN antibody.

Specification

Quantity

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