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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > [KO Validated] Beclin 1 Polyclonal Antibody

[KO Validated] Beclin 1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27321N-1 50ul / $395
APR27321N-2 100ul / $495
APR27321N-3 200ul / $595

[KO Validated] Beclin 1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27321N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] Beclin 1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 51kDa Observed MW: 60kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human Beclin 1 (NP_003757.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF,IP

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

Synonyms

BECN1; ATG6; VPS30; beclin1; beclin-1

Images

Western blot analysis of extracts of various cell lines, using Beclin 1 antibody.

Western blot analysis of extracts from normal (control) and Beclin 1 knockout (KO) 293T cells, using Beclin 1 antibody.

Immunohistochemistry of paraffin-embedded human breast cancer using Beclin 1 antibody.

Specification

Quantity

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