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PHKG2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27305N-1 50ul / $395
APR27305N-2 100ul / $495
APR27305N-3 200ul / $595

PHKG2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27305N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Carbohydrate metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PHKG2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 43kDa/46kDa Observed MW: 46kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PHKG2 (NP_000285.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Synonyms

PHKG2; GSD9C; phosphorylase kinase catalytic subunit gamma 2

Images

Western blot analysis of extracts of various cell lines, using PHKG2 antibody.

Specification

Quantity

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