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HBA1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27292N-1 50ul / $395
APR27292N-2 100ul / $495
APR27292N-3 200ul / $595

HBA1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27292N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HBA1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 15kDa Observed MW: 14kDa/25kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human HBA1 (NP_000508.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

Synonyms

HBA1; HBA-T3; HBH; hemoglobin subunit alpha

Images

Western blot analysis of extracts of various cell lines, using HBA1 antibody.

Immunofluorescence analysis of MCF7 cells using HBA1 antibody.

Specification

Quantity

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