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SIRT3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27278N-1 50ul / $395
APR27278N-2 100ul / $495
APR27278N-3 200ul / $595

SIRT3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27278N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SIRT3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 28kDa/43kDa Observed MW: 27kDa

Species Reactivity

Rabbit

Immunogen

A synthetic synthetic peptide of human SIRT3 (NP_036371.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:100 - 1:200

Product Description

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

Synonyms

SIRT3; SIR2L3; sirtuin 3

Images

Western blot analysis of extracts of various cell lines, using SIRT3 antibody.

Immunohistochemistry of paraffin-embedded rat kidney using SIRT3 antibody.

Immunofluorescence analysis of MCF-7 cells using SIRT3 antibody.

Specification

Quantity

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