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RNF7 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27273N-1 50ul / $395
APR27273N-2 100ul / $495
APR27273N-3 200ul / $595

RNF7 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27273N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RNF7 Polyclonal Antibody.

Molecular Weight

Calculated MW: 9kDa/10kDa/11kDa/12kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human RNF7 (NP_055060.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:20 - 1:50

Product Description

The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Synonyms

RNF7; CKBBP1; ROC2; SAG; RING-box protein 2

Images

Immunofluorescence analysis of MCF-7 cells using RNF7 antibody.

Specification

Quantity

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