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IKZF3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27259N-1 50ul / $395
APR27259N-2 100ul / $495
APR27259N-3 200ul / $595

IKZF3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27259N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Transcription Factors

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IKZF3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 29-58kDa Observed MW: 58kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human IKZF3 (NP_036613.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.

Synonyms

IKZF3; AIO; AIOLOS; ZNFN1A3; zinc finger protein Aiolos

Images

Western blot analysis of extracts of various cell lines, using IKZF3 Antibody.

Immunofluorescence analysis of MCF-7 cells using IKZF3 antibody.

Specification

Quantity

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