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MCP-1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27250N-1 50ul / $395
APR27250N-2 100ul / $495
APR27250N-3 200ul / $595

MCP-1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27250N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MCP-1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 11kDa Observed MW: 11kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human MCP-1 (NP_002973.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:100

Product Description

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

Synonyms

CCL2; GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF; C-C motif chemokine 2

Images

Western blot analysis of extracts of various cell lines, using CCL2 antibody.

Immunohistochemistry of paraffin-embedded human colon using MCP-1 antibody.

Immunohistochemistry of paraffin-embedded human stomach using MCP-1 antibody.

Specification

Quantity

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