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UIMC1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27235N-1 50ul / $395
APR27235N-2 100ul / $495
APR27235N-3 200ul / $595

UIMC1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27235N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>DNA Damage & Repair

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UIMC1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 17kDa/38kDa/61kDa/70kDa/79kDa Observed MW: 60kDa/80kDa/120kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human UIMC1 (NP_057374.3).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.

Synonyms

UIMC1; RAP80; X2HRIP110; BRCA1-A complex subunit RAP80

Images

Western blot analysis of extracts of various cell lines, using UIMC1 antibody.

Immunofluorescence analysis of GFP-RNF168 transgenic U2OS cells using UIMC1 antibody.

Specification

Quantity

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