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UCP1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27227N-1 50ul / $395
APR27227N-2 100ul / $495
APR27227N-3 200ul / $595

UCP1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27227N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Endocrine and metabolic diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UCP1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 33kDa Observed MW: 33kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human UCP1 (NP_068605.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.

Synonyms

UCP1; SLC25A7; UCP; uncoupling protein 1

Images

Western blot analysis of extracts of various cell lines, using UCP1 antibody.

Specification

Quantity

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