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SNCA Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27209N-1 50ul / $395
APR27209N-2 100ul / $495
APR27209N-3 200ul / $595

SNCA Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27209N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SNCA Polyclonal Antibody.

Molecular Weight

Calculated MW: 11kDa/13kDa/14kDa Observed MW: 16kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SNCA (NP_000336.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.

Synonyms

SNCA; NACP; PARK1; PARK4; PD1; alpha-synuclein

Images

Western blot analysis of extracts of various cell lines, using SNCA antibody.

Immunofluorescence analysis of MCF-7 cells using SNCA antibody.

Specification

Quantity

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