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PTPRE Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27203N-1 50ul / $395
APR27203N-2 100ul / $495
APR27203N-3 200ul / $595

PTPRE Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27203N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PTPRE Polyclonal Antibody.

Molecular Weight

Calculated MW: 71kDa/74kDa/80kDa Observed MW: 81kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PTPRE (NP_006495.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels.

Synonyms

PTPRE; HPTPE; PTPE; R-PTP-EPSILON; protein tyrosine phosphatase, receptor type E

Images

Western blot analysis of extracts of various cell lines, using PTPRE antibody.

Immunohistochemistry of paraffin-embedded rat brain using PTPRE antibody.

Immunohistochemistry of paraffin-embedded mouse brain using PTPRE antibody.

Specification

Quantity

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