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ALS2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27132N-1 50ul / $395
APR27132N-2 100ul / $495
APR27132N-3 200ul / $595

ALS2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27132N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ALS2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 42kDa/86kDa/183kDa Observed MW: 184kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ALS2 (NP_065970.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

ALS2; ALS2CR6; ALSJ; IAHSP; PLSJ; alsin

Images

Western blot analysis of extracts of various cell lines, using ALS2 antibody.

Specification

Quantity

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