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ACTL6B Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27115N-1 50ul / $395
APR27115N-2 100ul / $495
APR27115N-3 200ul / $595

ACTL6B Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27115N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Cell Type Marker

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ACTL6B Polyclonal Antibody.

Molecular Weight

Calculated MW: 46kDa Observed MW: 47-55kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ACTL6B (NP_057272.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Product Description

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants.

Synonyms

ACTL6B; ACTL6; BAF53B; arpNalpha; actin like 6B

Images

Western blot analysis of extracts of various cell lines, using ACTL6B antibody.

Immunohistochemistry of paraffin-embedded human kidney using ACTL6B antibody.

Immunohistochemistry of paraffin-embedded human kidney cancer using ACTL6B antibody.

Specification

Quantity

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