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VPS4A Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27103N-1 50ul / $395
APR27103N-2 100ul / $495
APR27103N-3 200ul / $595

VPS4A Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27103N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VPS4A Polyclonal Antibody.

Molecular Weight

Calculated MW: 48kDa Observed MW: 49kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human VPS4A (NP_037377.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100

Product Description

The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16; the gene for the other resides on chromosome 18.

Synonyms

VPS4A; SKD1; SKD1A; SKD2; VPS4; VPS4-1; vacuolar protein sorting 4 homolog A

Images

Western blot analysis of extracts of various cell lines, using VPS4A antibody.

Immunohistochemistry of paraffin-embedded human stomach using VPS4A antibody.

Immunohistochemistry of paraffin-embedded human lung using VPS4A antibody.

Specification

Quantity

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