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TES Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27101N-1 50ul / $395
APR27101N-2 100ul / $495
APR27101N-3 200ul / $595

TES Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27101N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TES Polyclonal Antibody.

Molecular Weight

Calculated MW: 46kDa/47kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human TES (NP_056456.1).

Cross Reactivity

Human,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.

Synonyms

TES; TESS; TESS-2; testin

Images

Immunohistochemistry of paraffin-embedded rat ovary using TES antibody.

Immunohistochemistry of paraffin-embedded human lung cancer using TES antibody.

Immunohistochemistry of paraffin-embedded human liver cancer using TES antibody.

Specification

Quantity

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