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GCA Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27094N-1 50ul / $395
APR27094N-2 100ul / $495
APR27094N-3 200ul / $595

GCA Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27094N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GCA Polyclonal Antibody.

Molecular Weight

Calculated MW: 24kDa Observed MW: 24kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human GCA (NP_036330.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.

Synonyms

GCA; GCL; grancalcin

Images

Western blot analysis of extracts of various cell lines, using GCA antibody.

Immunofluorescence analysis of A549 cells using GCA antibody.

Specification

Quantity

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