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COPS6 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27081N-1 50ul / $395
APR27081N-2 100ul / $495
APR27081N-3 200ul / $595

COPS6 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27081N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Ubiquitin

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality COPS6 Polyclonal Antibody.

Molecular Weight

Calculated MW: 36kDa Observed MW: 36kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human COPS6 (NP_006824.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.

Synonyms

COPS6; CSN6; MOV34-34KD; COP9 signalosome subunit 6

Images

Western blot analysis of extracts of various cell lines, using COPS6 antibody.

Immunofluorescence analysis of MCF7 cells using COPS6 antibody.

Specification

Quantity

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