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CYTH2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27044N-1 50ul / $395
APR27044N-2 100ul / $495
APR27044N-3 200ul / $595

CYTH2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27044N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYTH2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 46kDa Observed MW: 47kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CYTH2 (NP_059431.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

CYTH2; ARNO; CTS18; CTS18.1; PSCD2; PSCD2L; SEC7L; Sec7p-L; Sec7p-like; cytohesin-2

Images

Western blot analysis of extracts of various cell lines, using CYTH2 antibody.

Immunofluorescence analysis of U2OS cells using CYTH2 antibody.

Specification

Quantity

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