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CCNE2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27041N-1 50ul / $395
APR27041N-2 100ul / $495
APR27041N-3 200ul / $595

CCNE2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27041N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CCNE2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 41kDa/46kDa Observed MW: 47kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CCNE2 (NP_477097.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells.

Synonyms

CCNE2; CYCE2; cyclin E2

Images

Western blot analysis of extracts of Jurkat cells, using CCNE2 antibody.

Immunofluorescence analysis of MCF7 cells using CCNE2 antibody.

Specification

Quantity

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