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PRC1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27038N-1 50ul / $395
APR27038N-2 100ul / $495
APR27038N-3 200ul / $595

PRC1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27038N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRC1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 61kDa/66kDa/70kDa/71kDa Observed MW: 72kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PRC1 (NP_003972.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants.

Synonyms

PRC1; ASE1; protein regulator of cytokinesis 1

Images

Western blot analysis of extracts of various cell lines, using PRC1 antibody.

Immunofluorescence analysis of MCF7 cells using PRC1 antibody.

Specification

Quantity

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