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HYAL3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27022N-1 50ul / $395
APR27022N-2 100ul / $495
APR27022N-3 200ul / $595

HYAL3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27022N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HYAL3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 15kDa/18kDa/43kDa/46kDa Observed MW: 47kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human HYAL3 (NP_003540.2).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon.

Synonyms

HYAL3; HYAL-3; LUCA-3; LUCA3; hyaluronidase-3

Images

Western blot analysis of extracts of various cell lines, using HYAL3 antibody.

Specification

Quantity

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