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NELFE Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27018N-1 50ul / $395
APR27018N-2 100ul / $495
APR27018N-3 200ul / $595

NELFE Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27018N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NELFE Polyclonal Antibody.

Molecular Weight

Calculated MW: 40kDa/43kDa Observed MW: 43kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human NELFE (NP_002895.3).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6.

Synonyms

NELFE; D6S45; NELF-E; RD; RDBP; RDP; negative elongation factor E

Images

Western blot analysis of extracts of various cell lines, using NELFE antibody.

Immunofluorescence analysis of U2OS cells using NELFE antibody.

Specification

Quantity

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