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TNNI3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27007N-1 50ul / $395
APR27007N-2 100ul / $495
APR27007N-3 200ul / $595

TNNI3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27007N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TNNI3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 24kDa Observed MW: 26kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human TNNI3 (NP_000354.4).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

Synonyms

TNNI3; CMD1FF; CMD2A; CMH7; RCM1; TNNC1; cTnI; troponin I3, cardiac type

Images

Western blot analysis of extracts of various cell lines, using TNNI3 antibody.

Immunohistochemistry of paraffin-embedded human stomach using TNNI3 antibody.

Immunofluorescence analysis of mouse heart cells using TNNI3 antibody.

Specification

Quantity

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