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SSX2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR27001N-1 50ul / $395
APR27001N-2 100ul / $495
APR27001N-3 200ul / $595

SSX2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR27001N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SSX2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 21kDa/25kDa Observed MW: 22kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SSX2 (NP_783629.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X.

Synonyms

SSX2; CT5.2; CT5.2A; HD21; HOM-MEL-40; SSX; protein SSX2

Images

Western blot analysis of extracts of HeLa cells, using SSX2 antibody.

Immunohistochemistry of paraffin-embedded human colon carcinoma using SSX2 antibody.

Specification

Quantity

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