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PLOD2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26960N-1 50ul / $395
APR26960N-2 100ul / $495
APR26960N-3 200ul / $595

PLOD2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26960N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PLOD2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 49kDa/84kDa/87kDa Observed MW: 85kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PLOD2 (NP_891988.1).

Cross Reactivity

Human,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

PLOD2; BRKS2; LH2; TLH; procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

Images

Western blot analysis of extracts of rat kidney, using PLOD2 Antibody.

Specification

Quantity

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