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PDHB Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26957N-1 50ul / $395
APR26957N-2 100ul / $495
APR26957N-3 200ul / $595

PDHB Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26957N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Carbohydrate metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PDHB Polyclonal Antibody.

Molecular Weight

Calculated MW: 37kDa/39kDa Observed MW: 39kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PDHB (NP_000916.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene.

Synonyms

PDHB; PDHBD; PDHE1-B; PHE1B; pyruvate dehydrogenase (lipoamide) beta

Images

Western blot analysis of extracts of various cell lines, using PDHB antibody.

Specification

Quantity

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