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ASIP Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26893N-1 50ul / $395
APR26893N-2 100ul / $495
APR26893N-3 200ul / $595

ASIP Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26893N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Growth factors

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ASIP Polyclonal Antibody.

Molecular Weight

Calculated MW: 14kDa Observed MW: _

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ASIP (NP_001663.2).

Cross Reactivity

Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

IHC,IF

Dilution

IHC 1:50 - 1:100 IF 1:50 - 1:100

Product Description

In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.

Synonyms

ASIP; AGSW; AGTI; AGTIL; ASP; SHEP9; agouti-signaling protein

Images

Immunohistochemistry of paraffin-embedded human prostate cancer using ASIP antibody.

Immunohistochemistry of paraffin-embedded human gastric cancer using ASIP antibody.

Specification

Quantity

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