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FBXO32 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26869N-1 50ul / $395
APR26869N-2 100ul / $495
APR26869N-3 200ul / $595

FBXO32 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26869N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Heart

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FBXO32 Polyclonal Antibody.

Molecular Weight

Calculated MW: 30kDa/41kDa Observed MW: 42kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human FBXO32

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:1000

Product Description

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

FBXO32; Fbx32; MAFbx; F-box protein 32

Images

Western blot analysis of extracts of various cell lines, using FBXO32 antibody.

Specification

Quantity

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