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FANCL Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26863N-1 50ul / $395
APR26863N-2 100ul / $495
APR26863N-3 200ul / $595

FANCL Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26863N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>DNA Damage & Repair

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FANCL Polyclonal Antibody.

Molecular Weight

Calculated MW: 42kDa/43kDa Observed MW: 38kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human FANCL (NP_060532.2).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:200 - 1:2000 IHC 1:20 - 1:200

Product Description

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.

Synonyms

FANCL; FAAP43; PHF9; POG; E3 ubiquitin-protein ligase FANCL

Images

Western blot analysis of extracts of mouse thymus, using FANCL antibody.

Immunohistochemistry of paraffin-embedded mouse stomach using FANCL antibody.

Immunohistochemistry of paraffin-embedded human esophagus using FANCL antibody.

Specification

Quantity

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