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SURF1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR26821N-1 50ul / $395
APR26821N-2 100ul / $495
APR26821N-3 200ul / $595

SURF1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR26821N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Mitochondrial metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SURF1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 31kDa/33kDa Observed MW: 33kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SURF1 (NP_003163.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.

Synonyms

SURF1; CMT4K; surfeit locus protein 1

Images

Western blot analysis of extracts of various cell lines, using SURF1 antibody.

Immunohistochemistry of paraffin-embedded human colon carcinoma using SURF1 antibody.

Specification

Quantity

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